Phenylketonuria

Phenylketonuria (PKU):
A rare autosomal recessive disorder caused by deficiency of phenylalanine hydroxylase, leading to accumulation of phenylalanine → intellectual disability, seizures, hypopigmentation if untreated. Managed with low-phenylalanine diet.

Popular Posts

Colorful Copy to Clipboard HTML Code <div> <p>This is an example paragraph</p> </div> Copy
Post

Can I access the course materials after completing the certificate?

Yes, as long as you maintain your Coursera subscription, you’ll have continued access to all course materials, including updates and new content. Many graduates find it valuable to return to specific modules when applying concepts in their new roles. 📌 Skills with Coursera Google IT Automation with Python Professional Certificate 🎓
Post

Synthesis of Glucose Fromaminoacids

Synthesis of Glucose from Amino Acids (Gluconeogenesis) Definition:  Conversion of  glucogenic amino acids  into  glucose  via gluconeogenesis. Process: Glucogenic amino acids  (e.g., alanine, glutamine) are  deaminated  to form  pyruvate  or  TCA cycle intermediates  (e.g., oxaloacetate). These intermediates enter the  gluconeogenic pathway  in the  liver  (and kidney). Final product is  glucose , released into blood to maintain blood sugar. Example with real pathway : Alanine → Pyruvate → Oxaloacetate → Phosphoenolpyruvate → Glucose This is called the  glucose-alanine cycle . Key enzymes: Alanine transaminase (ALT) Pyruvate carboxylase PEP carboxykinase Fructose-1,6-bisphosphatase Glucose-6-phosphatase Short Answer: Glucogenic amino acids (e.g., alanine, glutamine) are deaminated to form pyruvate or TCA intermediates, which via gluconeogenesis in liver/kidney form glucose. Example: Alanine → Pyru...
Post